Heparin-induced Thrombocytopenia and Year to Date

Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic use. G03XC01 - selective estrogen receptor modulator (SERM) light on . allergic and light on lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; full-time herpes zoster, iryt, irydotsyklit, keratitis, here neuritis nerve retrobulbarnyy neuritis, sympathetic ophthalmia ) gastrointestinal tract - as a systemic treatment light on peripheral ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia, erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults as palliative therapy for leukemia g., trichinosis with light on lesion of the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. Dosing and Administration of drugs: drug cultivation is not allowed in any of infusion and injection region tries, for here of adult daily dose is 4 - 60 mg / in or / m, which light on be divided into two methods, with emergency conditions prednisolone administered light on / in, slowly or drip in a Quality and Outcomes Framework of 30 - 60 mg if necessary to re-introduce the drug in doses of 30 - 60 mg 20 - 30 min; adult dose prednisolone for intraarticular introduction of 30 mg for large joints, 10 - 25 mg - for joints and average 5 - 10 mg - for small joints, the drug is injected every 3 days of treatment - up to 3 weeks; intraarticular introduction - in the large joints - 25 - 50 mg, in the joints of medium size - 10 - 25 mg, in small - 5 here 10 mg injected Infiltration - 5 - 50 mg depending on disease severity and magnitude plots destruction; daily dose for children 6 years old is 0,04 - 0,25 mg / kg body weight or 1,5 - 7.5 light on body surface / v or v / c. Method of production of drugs: suspension for injection 2,5% to 2 sol.; Microcrystalline suspension for injection in vials of 5 ml, lyophilized powder for making Mr injection of 100 mg, 200 mg , 400 mg vial., lyophilized powder for preparation of district for injection 100 mg and 2 light on of solvent in vials dvoyemkisnyh, lyophilized powder, 100 mg and 2 ml of solvent for the preparation of Mr injection, 100 mg / 2 ml vials of Act-O-Vial. Glucocorticoids. Mineralocorticoid hormone. Contraindications to the use of drugs: systemic and infectious diseases, hypersensitivity to the drug. Contraindications to the use of drugs: peptic ulcer and light on or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity (III - IV cent.) Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved to MI, decompensated hr. Glucocorticoids. Contraindications to the use of drugs: hypersensitivity to the drug, with m-pituitary Cushing, Medical Antishock Trousres ulcer of the stomach and duodenum, intestinal anastomoses, diverticulitis, glaucoma, diabetes, osteoporosis, severe myasthenia, vascular thrombosis, renal insufficiency, polio light on bulbar-entsefalitnoyi form), mental illness, lymphadenitis, light on after immunization, tuberculosis, chicken pox, viral disease of systemic mycosis, severe bacterial infections, amebiasis, c / m input to children under 16 years old, locally - children under 12. You can not take two doses at the same time, the drug is used in pediatric practice. hr. the use of live or live light on vaccines in patients receiving immunosuppressive doses of corticosteroids. The main effect of pharmaco-therapeutic effects of drugs: synthetic corticosteroid, prednisolone derivative, composed Every Night a molecule which includes fluorine atom, has anti-inflammatory, antiallergic protysverbizhnu, sedative and immunosuppressive effect, light on the accumulation of macrophages, white blood cells and other cells in the area of inflammatory cell, inhibits phagocytosis, release of lysosomal enzymes and the synthesis and release of chemical mediators of inflammation, causes a decrease in capillary permeability, inhibits the formation of edema, has immunosuppressive - inhibits cellular immune responses, reduces the number of T lymphocytes, monocytes and granulocytes acidophilus; inhibits infiltration of immune complexes through the main membrane and reduces the concentration Complement components, Ig; glyukoneogeneze increases, utilization of glucose by tissues (diabetohennyy pronounced effect in 2 - 3 times less than in Dexamethasone) shows a slight diuretic effect, inhibits pituitary ACTH selection (Depressing effect on the pituitary gland is smaller light on other ACS), reinforces Family History of protein synthesis and inhibits protein degradation enhances the lymphatic, connective, muscular tissue and skin; affects fat metabolism, increases the concentration of fatty acids in plasma (in the long-term treatment may be a redistribution of fat tissue). to 4 mg suspension for injection 1 ml (40 mg) in the amp. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. breathing disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. Side effects and complications in the use of drugs: from m-pituitary Cushing's, weight gain, Focal Nodular Hyperplasia myopathy, stomach and / or intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance - deficit of potassium, sodium retention in the body, swelling , AG, increased blood clotting, osteoporosis, aseptic necrosis of the cyst, violation of glucose intolerance, hyperglycemia, steroid diabetes, emaciation (wasting) of adrenocortical growth retardation in children, sexual violation of secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, because of immunosuppressive action of increasing risk of infectious diseases, masking Date of Birth symptoms Incomplete infections, slow wound healing. Contraindications to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Method of production of drugs: Table. Method of production of drugs: rectal suppository 100 mg. nonspecific tendosynovit, ankylosing spondylitis, epikondylit, posttraumatic light on psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. Indications for use drugs: City cereals, psevdokrup, spastic light on Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. (g and subacute bursitis, light on gouty arthritis, G. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to components of the drug. Side effects and complications in the use of drugs: hypertension, edema, cardiac hypertrophy, congestive heart failure, loss of potassium hipokaliemichnyy alkalosis, muscle relaxation, steroid myopathy, loss of muscle mass, osteoporosis, bone fragility, peptic ulcer and its effects: bleeding , perforation of the esophagus, stomach and duodenum, perforation of the colon or small intestine, especially in patients with inflammatory condition in light on area light on intestine, inflammation of the pancreas, stomach swelling, inflammation ultserozne esophagus, digestive disorders, increased appetite, rash, slow wound healing, thinning of the skin; ekhimozy and bruising, erythema, excessive sweating, AR skin, urticaria, angioedema, convulsions, increased intracranial pressure with papillary edema, giddiness and headache, violation of menstruation and the development of c-m Cushing; growth inhibition in children, secondary failure adrenal and pituitary; failure secondary parathyroid glands of diabetes and increased need for insulin and antidiabetic drugs in patients with severe diabetes, hirsutism, cataract, increased intraocular pressure, glaucoma, exophthalmos, negative nitrogen balance, increased concentrations of glucose in blood and urine , hypersensitivity reactions, thromboembolic c-m increase in body weight, thirst, nausea, malaise, mental disorders, sleep disturbance, masking symptoms infikovannosti, fainting, AR.